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QuickView for SIX homeobox 5;jsessionid=2EF8A23F0C401155E2D4E12CA9E343A2;jsessionid=7554AB269C1EDE146125D9E006012C91 (gene)


Gene Symbol:
Six5 Mus musculus Mus musculus
Full name:
sine oculis-related homeobox 5
Synonyms:
Dmahp, MDMAHP, TrexBF, homeobox protein SIX5, DM locus-associated homeodomain protein homolog, sine oculis homeobox homolog 5, sine oculis-related homeobox 5 homolog
Genomic Location:
Chr 7: 19679893-19683694
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Pan troglodytes Bos taurus Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_011383
XR_001785498
XM_006539694
Protein Names
P70178



GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | developmental process involved in reproduction | eye development | negative regulation of skeletal muscle satellite cell proliferation | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cell differentiation | male gamete generation | positive regulation of cellular biosynthetic process | cellular process | regulation of skeletal muscle cell proliferation | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | gamete generation | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | regulation of skeletal muscle satellite cell proliferation | RNA biosynthetic process | cellular aromatic compound metabolic process | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | germ cell development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | reproduction | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | spermatid differentiation | cellular biosynthetic process | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | sensory organ development | regulation of cellular metabolic process | regulation of RNA metabolic process | multicellular organism reproduction | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | spermatid development | transcription, DNA-templated | camera-type eye development | regulation of transcription, DNA-templated | cell development | cellular macromolecule biosynthetic process | developmental process | spermatogenesis | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | sexual reproduction | lens development in camera-type eye | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | transcription factor complex | intracellular organelle | protein-containing complex | membrane-bounded organelle | nucleus | organelle | intracellular